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Osteoarthritis is the most common joint disease. While there are many analgesics to treat pain from OA, no drug has shown efficacy in treating the disease. Such a disease modifying drug, such as Humira for Rheumatoid Arthritis, could revolutionize the treatment of OA. VOLT01 is possibly the first and only DMOAD for OA.
This invention introduces a novel way to induce the growth of cartilage while also avoiding the adverse side effects associated with current, limited standard procedures, such as autografting and introducing high doses of growth hormone. This technology has the potential to revolutionize the way physicians approach cartilage related regeneration or treatment of cartilage related diseases.
Several recent studies suggest that the microbiome bacterial community of an individual’s gut may play a role in obesity by increasing or decreasing that individual’s energy harvesting efficiency of its caloric intake. Researchers propose the use of bacterial species that consume acetate as a means to reduce caloric absorption and treat obesity.